Mostrant de 1 a 6 de 6 notícies disponibles
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Targeting Dihydroceramide Desaturase 1 (Des1): Syntheses of Ceramide Analogues with a Rigid Scaffold, Inhibitory Assays, and AlphaFold2-Assisted Structural Insights Reveal Cyclopropenone PR280 as a Potent Inhibitor
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Probing Site-Selective Conjugation Chemistries for the Construction of Homogeneous Synthetic Glycodendriproteins
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Revealing 2-Dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as Sphingosine Kinase 2 inhibitors: some hints on the structural basis for selective inhibition
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
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Trifluoromethylation of Electron-Rich Alkenyl Iodides with Fluoroform-Derived "Ligandless" CuCF3
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Fluorinated triazole-containing sphingosine analogues