Mostrando 1 a 6 de 6 noticias disponibles
-
Targeting Dihydroceramide Desaturase 1 (Des1): Syntheses of Ceramide Analogues with a Rigid Scaffold, Inhibitory Assays, and AlphaFold2-Assisted Structural Insights Reveal Cyclopropenone PR280 as a Potent Inhibitor
-
Probing Site-Selective Conjugation Chemistries for the Construction of Homogeneous Synthetic Glycodendriproteins
-
Revealing 2-Dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as Sphingosine Kinase 2 inhibitors: some hints on the structural basis for selective inhibition
-
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
-
Trifluoromethylation of Electron-Rich Alkenyl Iodides with Fluoroform-Derived "Ligandless" CuCF3
-
Fluorinated triazole-containing sphingosine analogues